Curriculum Vitae
Current Position
May 2022 – present
Medical Doctor & Junior Research Group Leader
Institute of Human Genetics, University Hospital Heidelberg
Genome Sequencing Pilot Study to evaluate feasibility and scalability for genomic newborn screening. Clinical care and consulting of patients with suspected genetic disorders.
Professional Experience
Oct 2016 – May 2022
Medical Doctor, Department of General Pediatrics, Metabolism, Gastroenterology, Nephrology
Center for Child and Adolescent Medicine, Heidelberg
Clinical care of children and adolescents with congenital and acquired diseases. Research on genotype-phenotype correlations for rare neurometabolic disorders.
Oct 2018 – May 2022
Post-doctoral Researcher, Inborn Errors of Neurotransmitters and Pterins
Dietmar-Hopp Metabolic Center, Heidelberg
Exploring congenital disorders of neurotransmission with induced pluripotent stem cells to generate cerebral organoids.
Education
April 2023
Board-Certified Pediatrician
Ärztekammer Baden-Württemberg
July 2021
Master of Business Administration — Management and Leadership in Health Care
University of Applied Sciences, Neu-Ulm, Germany
Thesis: "Development of recommendations for the implementation and quality assurance of an innovative gene therapy approach as well as derivation of a cost calculation for an outpatient follow-up model." Grade: 1.7
July 2016
Medical Degree (Dr. med.) — Magna cum laude
Eberhard Karls Universität Tübingen, Germany
Doctoral thesis: "IΒζ, an atypical inhibitor of NF-κB-mediated cell death in glioblastoma." Hertie Institute for Clinical Brain Research, Laboratory for Molecular Neuro-Oncology. Clinical rotations in Germany, USA, UK, China, and Switzerland.
Funding & Grants (Competitively Acquired)
17,640 €
Fritz Thyssen Foundation Conference Funding
"Towards Genomic Newborn Screening in Germany: Opportunities, Risks, and Challenges"
20,000 €
Klinz Foundation Project Funding
"Human stem cell-based cerebral organoids for research of diagnostics and therapy of succinate-semialdehyde dehydrogenase deficiency"
10,000 €
APS Project Funding
"Investigation of the pathophysiology of primary neurotransmitter defects using induced pluripotent stem cells (iPS) and iPS-based cerebral organoids"
1,000 €
Innovation Award for Outstanding SSADH Research
SSADH Defizit e.V.
Physician Scientist Scholarship
Medical Faculty, University of Heidelberg
8,000 €
Project Funding (2 grants), SSADH Defizit e.V.
Structured course in organoid generation at LMU Munich (3,000 €) · "Immunohistochemical characterization of SSADH organoids" (5,000 €)
DAAD Scholarship
Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA
13,500 €
IZKF Scholarship
Medical Faculty, University of Tübingen (6,000 € personal budget · 7,500 € consumables)
Memberships & Service
Founding Member & Chairman, Young Metabolician Society (APS)
Improving educational opportunities and resources for young professionals in inherited metabolic disorders
Member, German Society of Human Genetics (GfH) · Association for Pediatric Metabolic (APS) · German Society of Pediatrics and Adolescent Medicine (DGKJ)
Publications
Full publication list: heikobrennenstuhl.com/publications · Google Scholar · ORCID · PubMed
Contact: heiko.brennenstuhl@med.uni-heidelberg.de
· Institute of Human Genetics, University Heidelberg, 69120 Heidelberg
· +49 (0) 6221 - 56 - 5087